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KMID : 0360119960180010109
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Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
1996 Volume.18 No. 1 p.109 ~ p.114
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Plasmacytoma of the gingiva : case report and review of literature
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이우정
김기정/김종국/김형준/차인호
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Abstract
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Plasmacytoma is one of the malignant neoplasm that originate in immunoglobulin-producing plasma cell, and occurrence in gingiva is known to be rare.
About 7% of all patients with plasma cell malignancies present with solitary lesions in bone or soft tissues. In 30% to 40% of patients, the disease progresses to mulitiple myeloma on long-term follow-up. The incidence of progression to multiple
myeloma
is higher in patients with a bone lesion as compared with an extramedullary lesion.
Several studies have shown a relatively favorable course for both these groups of patients, but many long-term studies have demonstrated the distinct difference in ultimate prognosis between patients with solitary lesions in bone and those with
extramedullay lesions.
The primary objective in the past has been to suppress the immune system to permit allotransplantation. But immunosuppressant also increases the incidence of malignant neoplasms in patients after allograft transplantation.
We treated a 15-year patient with plasmacytoma on gingiva who had received kidny transplantation & immunosuppressant therapy. We excised this lesion & perfomed radiotherapy and had a favorable result.
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